Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIG3 All Species: 12.42
Human Site: S948 Identified Species: 22.78
UniProt: P49916 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49916 NP_002302.2 1009 112907 S948 V R L Y L P P S T P D F S R L
Chimpanzee Pan troglodytes XP_511409 922 102716 Y871 D F S R L R R Y F V A F D G D
Rhesus Macaque Macaca mulatta XP_001113780 1009 112805 S948 V R L Y L P P S T P D F S R L
Dog Lupus familis XP_548265 991 110592 S930 V R L Y L P P S T P D F S R L
Cat Felis silvestris
Mouse Mus musculus P97386 1015 113000 P953 G V R L Y L P P S T P D F K R
Rat Rattus norvegicus NP_001012011 943 105425 N891 K K T E Q K L N D P S S R G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006215 902 101303 Y851 D F N K I R R Y F I A Y D G D
Frog Xenopus laevis NP_001082183 988 110688 I910 A N K T L L D I F T G V K L H
Zebra Danio Brachydanio rerio NP_001025345 752 84159 S701 V W E S Q E Q S F L N L K C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650187 806 90830 L755 T E P Q K A D L V F Y A N T N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27474 773 86292 K722 S I F S S S T K K N E K D V K
Sea Urchin Strong. purpuratus XP_786357 875 97201 N824 K K V K N E R N G N N S N S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P04819 755 84810 S704 L T A D L S L S P I Y K A G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.1 97.7 89.4 N.A. 87.3 82.4 N.A. N.A. 71.3 68.2 55.7 N.A. 34.9 N.A. 23.3 48.4
Protein Similarity: 100 91.1 98.8 92.2 N.A. 91.3 86.4 N.A. N.A. 78.9 79.6 64.9 N.A. 48.1 N.A. 39.3 62.9
P-Site Identity: 100 13.3 100 100 N.A. 6.6 6.6 N.A. N.A. 0 6.6 13.3 N.A. 0 N.A. 0 0
P-Site Similarity: 100 13.3 100 100 N.A. 20 20 N.A. N.A. 13.3 6.6 20 N.A. 6.6 N.A. 6.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 0 0 0 0 16 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 16 0 0 8 0 0 16 0 8 0 24 8 24 0 16 % D
% Glu: 0 8 8 8 0 16 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 16 8 0 0 0 0 0 31 8 0 31 8 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 8 0 8 0 0 31 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 0 8 0 0 8 0 16 0 0 0 0 0 % I
% Lys: 16 16 8 16 8 8 0 8 8 0 0 16 16 8 8 % K
% Leu: 8 0 24 8 47 16 16 8 0 8 0 8 0 8 24 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 0 8 0 0 16 0 16 16 0 16 0 8 % N
% Pro: 0 0 8 0 0 24 31 8 8 31 8 0 0 0 8 % P
% Gln: 0 0 0 8 16 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 24 8 8 0 16 24 0 0 0 0 0 8 24 8 % R
% Ser: 8 0 8 16 8 16 0 39 8 0 8 16 24 8 8 % S
% Thr: 8 8 8 8 0 0 8 0 24 16 0 0 0 8 8 % T
% Val: 31 8 8 0 0 0 0 0 8 8 0 8 0 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 24 8 0 0 16 0 0 16 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _